Intellau_Celistic
5'3 KHHV Mentalcel
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- Joined
- Aug 26, 2021
- Posts
- 166,468
SNP ID | Chr: Basepair Position | Gene | Effective Allele | Amino Acid Substitution | No.of Carriers | Beta±SE | P Value | maxLDL≥190 (%) |
---|---|---|---|---|---|---|---|---|
rs141502002 | 1:55524222 | PCSK9 | T | Arg469Trp | 1147 | 9.4±1.1 | 3.71×10–17 | 17.9 |
rs12713559 | 2:21229068 | APOB | A | Arg3558Cys | 366 | 9.9±2.0 | 6.32×10–7 | 15.3 |
rs5742904 | 2:21229160 | APOB | T | Arg3527Gln | 256 | 43.5±2.4 | 3.40×10–75 | 42.2 |
rs768563000 | 19:11217264 | LDLR | A | Glu240Ter | 34 | 20.3±6.5 | 1.8×10–3 | 26.5 |
rs151207122 | 19:11218157 | LDLR | T | Arg303Trp | 49 | 36.2±5.4 | 2.16×10–11 | 36.7 |
rs121908030 | 19:11218160 | LDLR | A | Asp304Tyr | 30 | 80.2±6.9 | 4.67×10–31 | 66.7 |
rs201573863 | 19:11231154 | LDLR | T | Pro699Leu | 51 | 44.0±5.3 | 1.03×10–16 | 51.0 |
rs137853964 | 19:11240278 | LDLR | A | Val827Ile | 328 | 12.6±2.1 | 1.67×10–9 | 18.0 |
Population | Group | Sample Size | Ref Allele | Alt |
---|
Population | Group | Sample Size | Ref Allele | Alt Allele |
---|---|---|---|---|
Total | Global | 199288 | C=0.999729 | T=0.000271 |
European | Sub | 169946 | C=0.999953 | T=0.000047 |
African | Sub | 4954 | C=0.9923 | T=0.0077 |
African Others | Sub | 176 | C=1.000 | T=0.000 |
African American | Sub | 4778 | C=0.9920 | T=0.0080 |
Asian | Sub | 6350 | C=0.9998 | T=0.0002 |
East Asian | Sub | 4502 | C=0.9998 | T=0.0002 |