Blackpill Heritability of personality.

[WorthlessSlavicShit]

"Yikes, inkwell. Do you finally understand? The problem is your personality, and just your personality. You know what to do, right? Quick, time for you to gain DNA manipulation superpowers and change your personality with it, just like Marvel wowzaa."

Human personality is 30–60% heritable according to twin and adoption studies. Hundreds of genetic variants are expected to influence its complex development, but few have been identified. We used a machine learning method for genome-wide association studies (GWAS) to uncover complex genotypic–phenotypic networks and environmental interactions. The Temperament and Character Inventory (TCI) measured the self-regulatory components of personality critical for health (i.e., the character traits of self-directedness, cooperativeness, and self-transcendence). In a discovery sample of 2149 healthy Finns, we identified sets of single-nucleotide polymorphisms (SNPs) that cluster within particular individuals (i.e., SNP sets) regardless of phenotype. Second, we identified five clusters of people with distinct profiles of character traits regardless of genotype. Third, we found 42 SNP sets that identified 727 gene loci and were significantly associated with one or more of the character profiles. Each character profile was related to different SNP sets with distinct molecular processes and neuronal functions. Environmental influences measured in childhood and adulthood had small but significant effects. We confirmed the replicability of 95% of the 42 SNP sets in healthy Korean and German samples, as well as their associations with character. The identified SNPs explained nearly all the heritability expected for character in each sample (50 to 58%). We conclude that self-regulatory personality traits are strongly influenced by organized interactions among more than 700 genes despite variable cultures and environments. These gene sets modulate specific molecular processes in brain for intentional goal-setting, self-reflection, empathy, and episodic learning and memory.

Uncovering the complex genetics of human character - Molecular Psychiatry

Human personality is 30–60% heritable according to twin and adoption studies. Hundreds of genetic variants are expected to influence its complex development, but few have been identified. We used a machine learning method for genome-wide association studies (GWAS) to uncover complex...

www.nature.com

Everything is heritable. Personality is no exception. Personality is hereditary, or passed down from one generation to the next via genetic information, and is therefore heritable. Heritability is the proportion of phenotypic variance in an attribute in a population due to genetic variance in that population. Behavioral genetics research—twin, adoption, and family studies—furnishes the empirical evidence necessary to decipher the relative contributions of genes and environment to personality traits. Although most research in this domain has been done using the Big Five personality constructs, personality traits as defined by different models seem to be heritable. Specifically, they tend to be heritable in the 40-50% range. There is evidence that personality change across age is heritable and that the heritability of traits is consistent across different cultures. Modern technological and methodological advances may allow future research to further delineate which genes predict which personality traits.

https://www.researchgate.net/publication/327190186_Heritability_of_Personality

According to twin studies, the Big Five personality traits have substantial heritable components explaining 40–60% of the variance, but identification of associated genetic variants has remained elusive. Consequently, knowledge regarding the molecular genetic architecture of personality and to what extent it is shared across the different personality traits is limited. Using genomic-relatedness-matrix residual maximum likelihood analysis (GREML), we here estimated the heritability of the Big Five personality factors (extraversion, agreeableness, conscientiousness, neuroticism and openness for experience) in a sample of 5011 European adults from 527 469 single-nucleotide polymorphisms across the genome. We tested for the heritability of each personality trait, as well as for the genetic overlap between the personality factors. We found significant and substantial heritability estimates for neuroticism (15%, s.e.=0.08, P=0.04) and openness (21%, s.e.=0.08, P<0.01), but not for extraversion, agreeableness and conscientiousness. The bivariate analyses showed that the variance explained by common variants entirely overlapped between neuroticism and openness (rG=1.00, P <0.001), despite low phenotypic correlation (r=−0.09, P <0.001), suggesting that the remaining unique heritability may be determined by rare or structural variants. As far as we are aware of, this is the first study estimating the shared and unique heritability of all Big Five personality traits using the GREML approach. Findings should be considered exploratory and suggest that detectable heritability estimates based on common variants is shared between neuroticism and openness to experiences.

Heritability estimates of the Big Five personality traits based on common genetic variants

 

[12 Years a Rotter]

pajeets are letting this thread sleep. i always knew personality was genentic, that's why criminal scum begets more criminals

 

[Asgard]

My personality tends to be boring, compared to the average male.

 

[Asgard]

 

[AsiaCel]

Not surprised, but it's interesting that my family members all have different personalities

 

[Asgard]

IT won't touch this

They will touch this with their own dicks.