Everyone that ever lived in it.
Think of it. Taking lives like ER has no meaning at all, it may have a political sense according to some losers on the internet, but in the end that is just vanity and deads take an hour to be forgotten by normal people. Saving a life has no meaning either, since the life you saved has a high probability to have as much meaning as yours, which means none. Reproduction has no meaning, it just ends up creating more meaningless individuals and lost souls questionning "Ho God, why does the world have no meaning ?". Even abstract creations such as art or intellectual discoveries are too limited by our human vanity, flaws and lack of meaning, and in the end they only serve a meaningless specie to cope and keep progressing in a meaningless void to infinity.
The things we consider "meaningful" have no meaning, they are just socially acceptable copes and mental comfort zones.
We need to live and die without a meaning. That's the greatest hardship of life.