LifeFuel Free Yourself From the Chains of Desire With Oxytocin Receptor Antagonists

[Hell]

Imagine waking up tomorrow and not feeling the pain of loneliness or the deep ache of wanting to be touched by the opposite sex or even the urge to jerk your dick off.
Now imagine doing this without interfering with your hormone levels or dealing with brainfog/weight gain/etc. like you get with SSRIs and such. I don't know about you guys but a lot of the suffering I experience on a daily basis comes from the constant reminder that I am an ugly freak and a certified biological failure. It gets in the way of life and hits me at random times when I'm just trying to get through the day. Evolution did this to goad our ancestors into mating but evolution didn't foresee modern technology.

There are drugs out there used in research that block the reception of oxytocin and basically turn you from incel to volcel. One of them, L-368,899 has been shown to basically make monkeys and rats lose all interest in the opposite sex with no other apparent change in lifestyle:

Peripherally Administered Non-peptide Oxytocin Antagonist, L368,899®, Accumulates in Limbic Brain Areas: A New Pharmacological Tool for the Study of Social Motivation in Non-Human Primates

Central administration of oxytocin (OT) antagonists inhibits maternal and sexual behavior in non-primates, providing the strongest experimental evidence that endogenous OT facilitates these behaviors. While there have been a few reports that ICV administration ...

www.ncbi.nlm.nih.gov

Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats - PubMed

In male rats, oxytocin impacts both sexual arousal and certain types of consummatory sexual behaviors. However, the role of oxytocin in the motivational aspects of sexual behavior has received limited attention. Given the role that oxytocin signaling plays in consummatory sexual behaviors, it...

pubmed.ncbi.nlm.nih.gov

The downside is since this is basically just a laboratory tool and there is no plan to market it to the public it is very expensive. But maybe IT or even the general public can spearhead something since they hate the thought of us being sexual beings so much. Just think IT, all of us rapists and pedophiles or whatever you like to imagine in your spare time being effectively sterilized. Make it happen.

 

[Deleted member 27249]

So basically just castrate yourself?

 

[MuslimCell]

the next step of this degenerate society is to castrate ugly male .what a life a fuel .

 

[CleverJester]

Imagine waking up tomorrow and not feeling the pain of loneliness or the deep ache of wanting to be touched by the opposite sex or even the urge to jerk your dick off.
Now imagine doing this without interfering with your hormone levels or dealing with brainfog/weight gain/etc. like you get with SSRIs and such. I don't know about you guys but a lot of the suffering I experience on a daily basis comes from the constant reminder that I am an ugly freak and a certified biological failure. It gets in the way of life and hits me at random times when I'm just trying to get through the day. Evolution did this to goad our ancestors into mating but evolution didn't foresee modern technology.

There are drugs out there used in research that block the reception of oxytocin and basically turn you from incel to volcel. One of them, L-368,899 has been shown to basically make monkeys and rats lose all interest in the opposite sex with no other apparent change in lifestyle:

Peripherally Administered Non-peptide Oxytocin Antagonist, L368,899®, Accumulates in Limbic Brain Areas: A New Pharmacological Tool for the Study of Social Motivation in Non-Human Primates

Central administration of oxytocin (OT) antagonists inhibits maternal and sexual behavior in non-primates, providing the strongest experimental evidence that endogenous OT facilitates these behaviors. While there have been a few reports that ICV administration ...

www.ncbi.nlm.nih.gov

Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats - PubMed

In male rats, oxytocin impacts both sexual arousal and certain types of consummatory sexual behaviors. However, the role of oxytocin in the motivational aspects of sexual behavior has received limited attention. Given the role that oxytocin signaling plays in consummatory sexual behaviors, it...

pubmed.ncbi.nlm.nih.gov

The downside is since this is basically just a laboratory tool and there is no plan to market it to the public it is very expensive. But maybe IT or even the general public can spearhead something since they hate the thought of us being sexual beings so much. Just think IT, all of us rapists and pedophiles or whatever you like to imagine in your spare time being effectively sterilized. Make it happen.

The goal of life is to ascend, pass on its genetics. Society wants you to remove that goal and turn you into a goaless tool to serve their interest. Literally.

 

[soymonkcel]

I think we want to feel satisfied, not to feel the ultimate melancholic experience derived from the lack of desire. Bit that's just my opinion.

Here I skipped the paywall if you want to read it completely. I'm reading it.

So basically just castrate yourself?

the next step of this degenerate society is to castrate ugly male .what a life a fuel .

It isn't castration. Castration/SSRIs comes with other behavioral and metabolic shit as @Hell said like getting fat or having less energy. This wouldn't present those problems. I have to read it fully, tho.

The goal of life is to ascend, pass on its genetics. Society wants you to remove that goal and turn you into a tool to serve their interest. Literally.

Ascension is a lie even for normies imo. I rather not suffer tbh. Still, I have to read the full study, because there is something off about it.

Although both drug and vehicle treated rats exhibited a preference for the female, treatment with an oxytocin receptor antagonist decreased the amount of time spent with the female. There were no differences between drug and vehicle treated rats in either general activity, exploratory behaviors, the amount of time spent near the stimulus male rat, or consummatory sexual behaviors.

According to the abstract, they still want to fuck. They just don't want to bond, as I understand it.

 

[MuslimCell]

It isn't castration. Castration/SSRIs comes with other behavioral and metabolic shit as @Hell said like getting fat or having less energy. This wouldn't present those problems. I have to read it fully, tho.

manipulating nature will come with consequences and side effect . you are a human not a rat btw . and no thanks i rather endure the sexual frustration and manage it then simply eliminating what makes me a man and a human .

 

[soymonkcel]

. Male rats exhibited higher levels of sexual arousal, as indicated by the occurrence of penile erections, following direct administration of OT [...].

OT makes you horny for sure.

Despite these findings, rats in the current study treated with an OT receptor antagonist were no different than vehicle treated rats in either overall levels of activity, as indicated by the total number of approach zone entries, or general exploratory behavior, as indicated by the latency to first visit the male and female associated end chambers. In addition, there were no differences between drug and vehicle treated rats in the amount of time spent in the male associated end chamber, which indicated that the drug's effect on sexual motivation was not due to a decrease in social motivation, as posited elsewhere (Hurtazo et al., 2008). In fact, only vehicle treated rats, and not rats treated with the OT receptor antagonist, spent significantly less time in the male associated chamber relative to chance. Collectively, these results indicate that the reduction in sexual motivation exhibited by rats treated with an OT receptor antagonist was not affected by alterations in activity, exploratory behavior, or sociality.

Sounds like they didn't get depressed (yes, there are ways to measure depressive behavior on lab rats).

However, in adult male rats, central administration of OT receptor antagonists have been shown to attenuate consummatory sexual behaviors, such as the frequency of mounts and intromissions, as well as the likelihood of ejaculation and the latency to ejaculation (Argiolas et al., 1988; Arletti et al., 1992; Gil et al., 2011). Although previous evidence indicates the dose of the drug used in the current study readily crosses the blood brain barrier in non-human primates (Boccia et al., 2007), we cannot rule out the possibility that either central administration of the OT antagonist or a higher dose of the drug is necessary to affect the consummatory sexual behaviors of male rats.

They were injecting the drug directly into their brains. It is not sure their effect on humans (yet).

However, it is also important to note that test male rats in the current study were given a 20-minute sexual motivation test immediately prior to the consummatory sexual behavior test. Previous research indicates that a brief 10–20 minute exposure to a sexually receptive female placed behind a barrier that prevents physical contact raises levels of testosterone in both male mice and rats (Amstislavskaya and Popova, 2004; Bonilla-Jaime et al., 2006) and facilitates copulatory behavior in male rats (de Jonge et al., 1992). In addition to the reflexive release of testosterone that occurs in males following exposure to sexually receptive females, endogenous levels of OT tend to rise in the presence of a sexually receptive female placed behind a perforated wall (Waldherr and Neumann, 2007). Conceivably, enhanced neuroendocrine responsiveness as a result of exposure to sexual stimuli may have overcome the effects of the OT receptor antagonist on consummatory sexual behavior

It lowers your libido, but if you are show porn or any other kind of sexual stimulus, you can still get horny. The rats fucked anyway because they got exposed to sexually receptive females.

There's a valuable lesson here: don't expose yourself to sexual stimulus, and you might feel better because you will be less aroused (it happens to me after 2 weeks of NoFap). Personally, I would try the drug out of curiosity after the real side effects have been discovered, but somehow I suspect I wouldn't like it.

manipulating nature will come with consequences and side effect . you are a human not a rat btw . and no thanks i rather endure the sexual frustration and manage it then simply eliminating what makes me a man and a human .

Agree. There are still things we don't know about this and it could end up being reaaaallly bad for us. I'll let others try it first for a while.

 

[Copexodius Maximus]

Oxytocin is important chemical to bond us to family members and friends.

 

[Hell]

Oxytocin is important chemical to bond us to family members and friends.

You won't have to worry about those once you're older

 

[Copexodius Maximus]

You won't have to worry about those once you're older

Just cut of all connections you have to other people theory.

 

[Genetic Dead End]

I need this.

 

[Ricecel X]

Just cut of all connections you have to other people theory.

this is an effective life strategy tbh

 

[TheNEET]

maby it'd help for my slumber party cravings

L-368,899 hydrochloride Supplier | CAS 160312-62-9 | L368899 | Tocris Bioscience

View and buy high quality L-368,899 hydrochloride from Tocris Bioscience. Potent, non-peptide oxytocin receptor antagonist. Cited in 4 publications.

www.tocris.com

 

[latin_elioth]

If it dont dimish my cognitive habilities I would give it a shot

 

[BlkPillPres]

Imagine waking up tomorrow and not feeling the pain of loneliness or the deep ache of wanting to be touched by the opposite sex or even the urge to jerk your dick off.
Now imagine doing this without interfering with your hormone levels or dealing with brainfog/weight gain/etc. like you get with SSRIs and such. I don't know about you guys but a lot of the suffering I experience on a daily basis comes from the constant reminder that I am an ugly freak and a certified biological failure. It gets in the way of life and hits me at random times when I'm just trying to get through the day. Evolution did this to goad our ancestors into mating but evolution didn't foresee modern technology.

There are drugs out there used in research that block the reception of oxytocin and basically turn you from incel to volcel. One of them, L-368,899 has been shown to basically make monkeys and rats lose all interest in the opposite sex with no other apparent change in lifestyle:

Peripherally Administered Non-peptide Oxytocin Antagonist, L368,899®, Accumulates in Limbic Brain Areas: A New Pharmacological Tool for the Study of Social Motivation in Non-Human Primates

Central administration of oxytocin (OT) antagonists inhibits maternal and sexual behavior in non-primates, providing the strongest experimental evidence that endogenous OT facilitates these behaviors. While there have been a few reports that ICV administration ...

www.ncbi.nlm.nih.gov

Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats - PubMed

In male rats, oxytocin impacts both sexual arousal and certain types of consummatory sexual behaviors. However, the role of oxytocin in the motivational aspects of sexual behavior has received limited attention. Given the role that oxytocin signaling plays in consummatory sexual behaviors, it...

pubmed.ncbi.nlm.nih.gov

The downside is since this is basically just a laboratory tool and there is no plan to market it to the public it is very expensive. But maybe IT or even the general public can spearhead something since they hate the thought of us being sexual beings so much. Just think IT, all of us rapists and pedophiles or whatever you like to imagine in your spare time being effectively sterilized. Make it happen.

JFL castrating yourself is an admission of defeat, its not a win, its a self imposed loss, I'd become a rapist before I castrate myself, I'd make society kill me

 

[Autismus Maximus]

You can shove your chemical lobotomy so far up your ugly ass it counts as taking a pill again.

 

[Mr Joyboy]

 

[Hell]

If you're against it you're probably some early 20s hopecel.
Sad

 

[EyesAreSoCold]

Imagine waking up tomorrow and not feeling the pain of loneliness or the deep ache of wanting to be touched by the opposite sex or even the urge to jerk your dick off.
Now imagine doing this without interfering with your hormone levels or dealing with brainfog/weight gain/etc. like you get with SSRIs and such. I don't know about you guys but a lot of the suffering I experience on a daily basis comes from the constant reminder that I am an ugly freak and a certified biological failure. It gets in the way of life and hits me at random times when I'm just trying to get through the day. Evolution did this to goad our ancestors into mating but evolution didn't foresee modern technology.

There are drugs out there used in research that block the reception of oxytocin and basically turn you from incel to volcel. One of them, L-368,899 has been shown to basically make monkeys and rats lose all interest in the opposite sex with no other apparent change in lifestyle:

Peripherally Administered Non-peptide Oxytocin Antagonist, L368,899®, Accumulates in Limbic Brain Areas: A New Pharmacological Tool for the Study of Social Motivation in Non-Human Primates

Central administration of oxytocin (OT) antagonists inhibits maternal and sexual behavior in non-primates, providing the strongest experimental evidence that endogenous OT facilitates these behaviors. While there have been a few reports that ICV administration ...

www.ncbi.nlm.nih.gov

Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats - PubMed

In male rats, oxytocin impacts both sexual arousal and certain types of consummatory sexual behaviors. However, the role of oxytocin in the motivational aspects of sexual behavior has received limited attention. Given the role that oxytocin signaling plays in consummatory sexual behaviors, it...

pubmed.ncbi.nlm.nih.gov

The downside is since this is basically just a laboratory tool and there is no plan to market it to the public it is very expensive. But maybe IT or even the general public can spearhead something since they hate the thought of us being sexual beings so much. Just think IT, all of us rapists and pedophiles or whatever you like to imagine in your spare time being effectively sterilized. Make it happen.

Ye I wouldn't do it, I have no "copes" anyway. So instead of being bored with some periods of frustration and a little relief from masturbation, I'd just be bored 100% of the time.

 

[Deleted member 16390]

The goal of life is to ascend, pass on its genetics. Society wants you to remove that goal and turn you into a goaless tool to serve their interest. Literally.

Yes for a fully functioning man. It's the 4 Ps.
Purpose = Provide,Protect, Procreate.

Even according to christian teaching that is the first commandment God gave to Adam and Eve " be fruitful and multiply".
But north americans whiteys birth rate had been under 2.1 for decades, that is why I have strong doubts when many of these whiteys claimed to be followers of God.

 

[junkDNAonly]

Imagine waking up tomorrow and not feeling the pain of loneliness or the deep ache of wanting to be touched by the opposite sex or even the urge to jerk your dick off.
Now imagine doing this without interfering with your hormone levels or dealing with brainfog/weight gain/etc. like you get with SSRIs and such. I don't know about you guys but a lot of the suffering I experience on a daily basis comes from the constant reminder that I am an ugly freak and a certified biological failure. It gets in the way of life and hits me at random times when I'm just trying to get through the day. Evolution did this to goad our ancestors into mating but evolution didn't foresee modern technology.

There are drugs out there used in research that block the reception of oxytocin and basically turn you from incel to volcel. One of them, L-368,899 has been shown to basically make monkeys and rats lose all interest in the opposite sex with no other apparent change in lifestyle:

Peripherally Administered Non-peptide Oxytocin Antagonist, L368,899®, Accumulates in Limbic Brain Areas: A New Pharmacological Tool for the Study of Social Motivation in Non-Human Primates

Central administration of oxytocin (OT) antagonists inhibits maternal and sexual behavior in non-primates, providing the strongest experimental evidence that endogenous OT facilitates these behaviors. While there have been a few reports that ICV administration ...

www.ncbi.nlm.nih.gov

Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats - PubMed

In male rats, oxytocin impacts both sexual arousal and certain types of consummatory sexual behaviors. However, the role of oxytocin in the motivational aspects of sexual behavior has received limited attention. Given the role that oxytocin signaling plays in consummatory sexual behaviors, it...

pubmed.ncbi.nlm.nih.gov

The downside is since this is basically just a laboratory tool and there is no plan to market it to the public it is very expensive. But maybe IT or even the general public can spearhead something since they hate the thought of us being sexual beings so much. Just think IT, all of us rapists and pedophiles or whatever you like to imagine in your spare time being effectively sterilized. Make it happen.

just become sexless drone theory. Not gonna give up one of my only copes jfl

 

[Deleted member 14218]

Imagine waking up tomorrow and not feeling the pain of loneliness or the deep ache of wanting to be touched by the opposite sex or even the urge to jerk your dick off.
Now imagine doing this without interfering with your hormone levels or dealing with brainfog/weight gain/etc. like you get with SSRIs and such. I don't know about you guys but a lot of the suffering I experience on a daily basis comes from the constant reminder that I am an ugly freak and a certified biological failure. It gets in the way of life and hits me at random times when I'm just trying to get through the day. Evolution did this to goad our ancestors into mating but evolution didn't foresee modern technology.

There are drugs out there used in research that block the reception of oxytocin and basically turn you from incel to volcel. One of them, L-368,899 has been shown to basically make monkeys and rats lose all interest in the opposite sex with no other apparent change in lifestyle:

Peripherally Administered Non-peptide Oxytocin Antagonist, L368,899®, Accumulates in Limbic Brain Areas: A New Pharmacological Tool for the Study of Social Motivation in Non-Human Primates

Central administration of oxytocin (OT) antagonists inhibits maternal and sexual behavior in non-primates, providing the strongest experimental evidence that endogenous OT facilitates these behaviors. While there have been a few reports that ICV administration ...

www.ncbi.nlm.nih.gov

Administration of an oxytocin receptor antagonist attenuates sexual motivation in male rats - PubMed

In male rats, oxytocin impacts both sexual arousal and certain types of consummatory sexual behaviors. However, the role of oxytocin in the motivational aspects of sexual behavior has received limited attention. Given the role that oxytocin signaling plays in consummatory sexual behaviors, it...

pubmed.ncbi.nlm.nih.gov

The downside is since this is basically just a laboratory tool and there is no plan to market it to the public it is very expensive. But maybe IT or even the general public can spearhead something since they hate the thought of us being sexual beings so much. Just think IT, all of us rapists and pedophiles or whatever you like to imagine in your spare time being effectively sterilized. Make it happen.

this is the shit i been searching for and i theorized about this in one of my latest threads