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BRO NO WAY

Adam_was_lonley

Adam_was_lonley

Self-banned
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Joined
Aug 12, 2023
Posts
125
THERE AINT NO FUCLING WAAAAAAAAYAYU BROL'O/DSFBLDKFB'LFKB'DLNBS'DLFKNBSDLFBD/FLBSDLFBNEPOR ERG E9R ERG'RG'DFG'LB'LF'LB'LFB'L
FB
GFB
FB
RS
RT
;R I HA
 
Inceldom Discussed
 
Half-Attempt:

  • The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008]

1692998216714

1000Genomes_30x Global Study-wide6404G=0.5934A=0.4066
1000Genomes_30x African Sub1786G=0.7116A=0.2884
1000Genomes_30x Europe Sub1266G=0.4542A=0.5458
1000Genomes_30x South Asian Sub1202G=0.5957A=0.4043
1000Genomes_30x East Asian Sub1170G=0.5803A=0.4197
1000Genomes_30x American Sub980G=0.570A=0.430

  • Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

1692998368443
 
Did chad steal your oneitis?
 

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