Most trans people suffer a form of BDD, GID. In most cases doctors refuse to treat people with BDD by pandering to their delusions, e.g. someone is depressed about their right leg not being "theirs" and wants it amputated. Doctors won't.
Yet for some reason, despite it being exactly the same, when it comes to "gender" and "feeling like the opposite sex", ((psychiatrists)) demand that their patients get put on hormones and begin to transition. Men being put on estrogen causes RADICAL, and I mean really RADICAL changes to behaviour and psyche which reinforces their belief that they really are women in mens bodies.
I remember an interesting post from a guy who got addicted to taking estrogen, and he described it in detail. He said he suddenly started developing these very strong sexual fantasies about getting fucked by men, despite being objectively straight in his sexual orientation his whole life. He started taking estrogen as part of an out of control cross dressing kink, and it developed into very strong fantasies about getting dominated and fucked by men, despite it also simultaneously grossing him out because he was still "straight".