After 25 the problem is living with the socioeconomic consequences of growing up ugly and unwanted. Not getting laid is just one part of it.
If you grow up ugly and end up friendless at 18 you're pretty much doomed. everyone needs a support network to progress and succeed in life. Not just romantically but professionaly and academically as well. A guy who has friends and is well liked will enjoy going to class and sitting down to study with his friends, while the reject fears walking into the classroom after being a victim of violence in it and is unable to focus and retain the information presented by the teacher or professor. Did you know most people get their jobs through networking? Most job openings aren't published. Only bottom feeders like us have to apply through websites like indeed. These are just some examples of how being friendless in your youth fucks you over in adulthood.
Another problem that is rarely mentioned here is the lack of life experience. When you meet new people and get to know them you learn more about how life works and what works and doesn't when interacting with people. Trying to make friends at age 20 and beyond without these skills isn't going to work, unless you get lucky and run into some very tolerant people.
if you early life was shit you will probably end up poor, working a shit job and friendless in your 30s. Youngcels here need to make an effort and try to build a social circle, it's the only way to escape