The Only Black Truth Forum

[DiabloStanley91]

Literally this forum is the only truthful forum that deals with men's issues. I would like to post more here but i'm so bad rotting i just can't bro i have fucking acid reflux disease now from vomitting 20 times in the course of 2 months from whiskey + rum + coke/pepsi and some beer. I'm vomitmaxxing for real wtf idk anymore how to cope but this place is the most real shit i;ve seen i'll always read your posts and i respect you guys. The blackpill is everywhere.

Some guys like that animecel2d guys has over 612days active and over 100k posts you are awesome dude ( -> even if it's just one guy or multiple guys who use the account idc it's stil cool) and that zero guy too . I'm 31 so it's been ovER for quite some time for me but i'll see what i can do

Anyhow Tired of the gaslight of normies and cancer society

 

[wereq]

i have fucking acid reflux disease now from vomitting 20 times in the course of 2 months from whiskey + rum + coke/pepsi and some beer. I'm vomitmaxxing

I have this disease too. Its absolutely brutal and destroys life. It certainly destroyed my life. You might want to go to a GI specialist and even a surgeon.

 

[wereq]

I'm 31 so it's been ovER for quite some time for me but i'll see what i can do

I'm also 31 and its over for me too! Holy shit are you a clone of me?

 

[DiabloStanley91]

Nah bro i'm from eastern europe i'm a skinny fat loser

 

[Intellau_Celistic]

I had this problem when I was a young child. It was inherited from Mother(My other parent wasn't affected at all).

Urea or carbamide is synthesized in the body of many organisms as part of the urea cycle. It is the final degradation product of protein and amino acid metabolism. Urea is found in blood and is excreted by the kidney as a component of urine. Besides its role as carrier of waste nitrogen, urea also plays a role in the countercurrent exchange system of the nephrons, allowing for re-absorption of water and critical ions from the excreted urine. Cayman’s Urea Assay provides a convenient method for detecting urea in plasma, serum, and urine. In this assay, urease catalyzes the hydrolysis of urea into carbon dioxide and ammonia. Ammonia reacts with the detector resulting in a fluorescent product. Fluorescence is analyzed with an excitation wavelength of 405-415 nm and an emission wavelength of 470-480 nm.

My illness was cured through the use of probiotics.

The role of the nuclear genome in maintaining the stability of the mitochondrial genome (mtDNA) is incompletely known. mtDNA sequence variants can exist in a state of heteroplasmy, which denotes the coexistence of organellar genomes with different sequences. Heteroplasmic variants that impair mitochondrial capacity cause disease, and the state of heteroplasmy itself is deleterious. However, mitochondrial heteroplasmy may provide an intermediate state in the emergence of novel mitochondrial haplogroups. We used genome-wide genotyping data from 982,072 European ancestry individuals to evaluate variation in mitochondrial heteroplasmy and to identify the regions of the nuclear genome that affect it. Age, sex, and mitochondrial haplogroup were associated with the extent of heteroplasmy. GWAS identified 20 loci for heteroplasmy that exceeded genome-wide significance. This included a region overlapping mitochondrial transcription factor A (TFAM), which has multiple roles in mtDNA packaging, replication, and transcription. These results show that mitochondrial heteroplasmy has a heritable nuclear component.

Mitochondria carry multiple copies of their own genome organized into nucleoids, which include the nuclear-encoded DNA polymerase γ (POLG) and transcription factor A (TFAM)19. TFAM also helps maintaining mitochondrial DNA (mtDNA) integrity. We previously reported that H. pylori induces mtDNA mutations in gastric epithelial cells, also observed in gastritis patients, indicating an early occurrence of mtDNA instability during disease progression20. H. pylori also impairs mtDNA repair pathways.

Mitochondria are essential organelles not only responsible for energy production but also involved in apoptosis, calcium homeostasis, lipids and amino acids metabolism. Targeting mitochondria has emerged as a key strategy for bacteria to hijack host cells physiology and promote infection1,2. However, the underlying mechanisms and their relevance to disease remain to a great extent unresolved. Virulence factors of both intracellular and extracellular bacteria are secreted in the host cells and may interact with mitochondria, leading to modulation of mitochondrial function and ultimately promoting pathogenesis3,4,5. Mitochondria have also been reported as modulators of cellular antibacterial immunity and inflammatory response6. Helicobacter pylori is a human gastric pathogen and a major risk factor for gastric cancer7,8. H. pylori damages gastric cells introducing genetic instability and mitochondrial dysfunction, which largely contribute to the infection-associated pathogenicity9,10,11,12.

Mitochondria carry multiple copies of their own genome organized into nucleoids, which include the nuclear-encoded DNA polymerase γ (POLG) and transcription factor A (TFAM)19. TFAM also helps maintaining mitochondrial DNA (mtDNA) integrity. We previously reported that H. pylori induces mtDNA mutations in gastric epithelial cells, also observed in gastritis patients, indicating an early occurrence of mtDNA instability during disease progression20. H. pylori also impairs mtDNA repair pathways21.

 

[DenHaag]

damn son sorry to hear ... back when i drank my guts out I found that after some starvation diet, yogurt helped my recovery .. whiskey and coke will scrape out the intestines of the bioflora they need ... iono ymmv ... stay in the fight yo

 

[NoMoreHope]

but i'm so bad rotting i just can't bro i have fucking acid reflux disease now from vomitting 20 times in the course of 2 months from whiskey + rum + coke/pepsi and some beer.

High iq. Did u quitted drink? U should order more online tbh take care