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TL;DR : Title
(Depression means a reduction in genetic fitness, not clinical depression)
Hybrid vigor is not applicable to humans, not only this but there is no research to support it, and there is research to show outbreeding depression is a real thing, without turning this into a long post with links nobody is going to click anyway.
Outbreeding depression - Wikipedia
en.m.wikipedia.org
(Depression means a reduction in genetic fitness, not clinical depression)
Outbreeding depression manifests in two ways:
- Generating intermediate genotypes that are less fit than either parental form. For example, selection in one population might favor a large body size, whereas in another population small body size might be more advantageous, while individuals with intermediate body sizes are comparatively disadvantaged in both populations. As another example, in the Tatra Mountains, the introduction of ibex from the Middle East resulted in hybrids which produced calves at the coldest time of the year.[4]
- Breakdown of biochemical or physiological compatibility. Within isolated breeding populations, alleles are selected in the context of the local genetic background. Because the same alleles may have rather different effects in different genetic backgrounds, this can result in different locally coadapted gene complexes. Outcrossing between individuals with differently adapted gene complexes can result in disruption of this selective advantage, resulting in a loss of fitness.
In biology, a hybrid is the offspring resulting from combining the qualities of two organisms of different varieties, species or genera through sexual reproduction.
Humans are not a different species or genera, “variety” is a botanical term that refers to different plant species.Hybrid vigor is not applicable to humans, not only this but there is no research to support it, and there is research to show outbreeding depression is a real thing, without turning this into a long post with links nobody is going to click anyway.