lifefuel
Anti-White Propagandist
★★★★★
- Joined
- Nov 12, 2017
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She'd easily find a partner if she went for someone other than 6'4 9/10 millionaire chads
She'd easily find a partner if she went for someone other than 6'4 9/10 millionaire chads
She'd easily find a partner if she went for someone other than 6'4 9/10 millionaire chads
She'd easily find a partner if she went for someone other than 6'4 9/10 millionaire chads
She's talking about ugly foids like herself and not some short ugly ass niggers that want her number.
She's talking about ugly foids like herself and not some short ugly ass niggers that want her number.
chads
Senile plaques (SP) and neurofibrillary tangles (NFT) are the major histopathological changes that occur in Alzheimer's disease (AD). How these two different types of lesions are related to each other and to the dementia of AD is unknown. Recent studies lead to paradoxical conclusions: NFT and neuronal alterations such as synapse loss are much more closely related to the symptoms of dementia than are SP. However, mutations in the beta-amyloid protein of SP have been found in some patients with familial AD, suggesting that an abnormality in amyloid causes the development of SP, NFT and AD dementia. Examination of transgenic animals that produce amyloid precursor protein (APP), or altered forms of APP, may lead to the development of an animal model of AD, and ultimately to answers that link amyloid production to neuronal alterations, and cognitive impairments.
| Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|
| Population | Group | Sample Size | Ref Allele | Alt Allele |
|---|---|---|---|---|
| Total | Global | 10618 | G=0.59314 | A=0.40686, T=0.00000 |
| European | Sub | 8276 | G=0.5168 | A=0.4832, T=0.0000 |
| African | Sub | 1406 | G=0.9587 | A=0.0413, T=0.0000 |
| African Others | Sub | 54 | G=0.94 | A=0.06, T=0.00 |
| African American | Sub | 1352 | G=0.9593 | A=0.0407, T=0.0000 |
| Asian | Sub | 46 | G=0.91 | A=0.09, T=0.00 |
| East Asian | Sub | 32 | G=0.88 | A=0.12, T=0.00 |
Many of the implicated genes are involved in neuronal function: DCC, APBA1, PRR7, ZFHX3, HCRTR1, NEGR1, MEF2C, SHANK3 and ATXN2L (see Supplementary Note for the GeneCards summaries).
In conclusion, we conducted a meta-analysis GWAS and GWGAS for intelligence, including 13 cohorts and 78,308 individuals. We confirmed three loci and 12 genes, and identified 15 novel genomic loci and 40 novel genes for intelligence. Pathway analysis demonstrated the involvement of genes regulating cell development. We showed genetic overlap with several neuropsychiatric and metabolic disorders. These findings provide starting points for understanding the molecular neurobiological mechanisms underlying intelligence, one of the most investigated traits in humans
rs11138902 APBA1 intronic 9q21.11 a g 0.54 5.49 4.12E-08 +++++-++ 78307 1
thisShe's talking about ugly foids like herself and not some short ugly ass niggers that want her number.
this
We win, but at at what price?It's never coherent, so we win again.





