I used to be a polysubstance addict. I am now 6 months sober. I remember playing Chivalry: Medieval Warfare on an absolute heck tonne of acid. Each tab wasn't measured but it was guessed to be at least 80ug per tab. I was maybe 5 tabs in and I was seeing multicoloured after images of the sword swings and the game screen was growing larger than the size of the monitor, like the whole experience was sucking me in.
I had another great experience on 14 shrooms I handpicked myself. I was playing DotA 2 and all the colours were so vibrant and the trees were popping out of the screen. Everything was shiny and sparkly and psychedelic drugs + videogames = the bomb.
Eventually all the weed I was smoking and crazy shit I was doing was making me depressed. I was also coughing up black shit from smoking like, 64 bongs a day. The whole whacky experience of weed withdrawal (sweating, crazy dreams and chronic fatigue) scared me into quitting all together.