Holy shit, that image captures my life. But it's one of those "chicken or egg" questions, because I think my poor lifestyle is largely a result of failure of all differing sorts (social + professional). It's not that I didn't try, it's that I just couldn't hack it so became doomed to this lifestyle. I do have some mild hope of breaking out of it, but we'll see.
Anyway, depression is no joke. I got to a point of being so depressed two months ago that I literally became retarded and the spiritual and psychic pain was so unendurable that I came to understand how people can come to off themselves. Fortunately I'm afraid of death so I sought medication.
I will say this: I've seen serious arguments made that most of the things in that image contribute to depression, but I don't understand why weed is included in there. Smoking weed is to depression what taking aspirin is to chronic migraines: temporary relief. For example, one notorious aspect of having serious depression is anhedonia, the inability to feel pleasure. Not only do the depressed lose interest in their sources of fun, but even if they force themselves to engage in those things there's a good chance they won't derive pleasure from it. Well, smoking a good hybrid strain of cannabis always cured my anhedonia so that I could actually derive pleasure from vidya or listening to music or whatever. Cannabis is god's gift to man, IMO.