Serious Drugs with a high chance of OD on the first try?

[Dunkelheit]

Don't leave me hanging

 

[EthnicelNL]

Ketamine

 

[blickpall]

Do enough of anything and it will kill you. Even eating carrots excessively will kill you. Drink enough water and it will kill you. Stop being melodramatic, though. If you're asking questions like this, you're not interested in ending it, you're interested in getting high and getting attention.