Except having a neurological disease which impedes your ability to function socially fucks you over in fields of interaction which are less dependent on looks, such as hanging out with men on the same level of the looks/status totem pole as you and getting any sort of normie status to begin with. You become socially unaware and absent, you have no clue when something complex and social is going on with the people around you until you hear it being talked about or it happens extremely plainly in front of your face, making inroads into low-tier normie groups or reddit failed normie groups becomes 100 times harder, shitty busywork employment for unattractive low-status males becomes harder to get and harder to keep because your weird mannerisms make it look like you don't know your place as a sub-5 male, and you usually can't even betabuxx if you get a lot of money because even getting a fat roastie to use you for money becomes several times harder.
Being ugly is bad, but autism amplifies it.