Brutal [NTpill]Genetic Overlap Between Schizophrenia & Height

[DarkStar]

This 2014 study analyzed 100'000 clumped SNPs, finding that around 50 SNPs overlap substantially between that of height & schizophrenia. Interestingly, the estimated number for this was only around 21, meaning that the results were 2x higher than the prediction.

The number of suggestive SNPs in the overlap of the two traits was 51 when the expected number under a random sharing was estimated to be 21.32.

The number of clumped SNPs in the overlap, as obtained using NIEHS tag SNPs (see Web Resources), was estimated to be 9. Assuming a Poisson distribution for the number of overlap clumped SNPs, the observed number (9) is significantly larger (p = 2.6 × 10−4) than the number expected (2.03)

The genetic overlap between schizophrenia and height - PMC

Epidemiological studies suggest that height and schizophrenia risk are inversely correlated. These findings might arise because i) height and schizophrenia share genetic variants and ii) the effects of these shared variants are in opposite direction ...

pmc.ncbi.nlm.nih.gov

Furthermore, this study found over 100 genes which are heavily associated with that of schizophrenia & height.

(55% sign-concordant) and 142 genes statistically associated with both SCZ and height.

The study also found strong correlations with nine genomic regions, with also a shared "genetic signal" within the 6 MHC-regions which was partially found to be explained by a genetic overlap with that of lymphocytes.

Seemingly, the study also found this out:

An epidemiological study by Zammit et al on 1.3 million Swedish males reported a 15% increase in schizophrenia (SCZ) prevalence in males of below-average height1.

Genetic overlap between schizophrenia and height implicates pituitary and immune response

Shorter stature has been phenotypically linked to increased prevalence of schizophrenia (SCZ)[1][1]. Using genome-wide genetic data, we studied the SCZ-height relationship on a genetic level. We identified 22 independent lead SNPs (55% sign-concordant) and 142 genes statistically associated with...

www.medrxiv.org

Which further correlates & ties into this:

Tall subjects had an approximately 15% reduction in risk compared with short subjects (adjusted HR = 0.85, 95% CI: 0.80-0.92).

 

[Grodd]

Another day another Blackpill

 

[veryrare]

Based, Saved.

@WorthlessSlavicShit

 

[Doesitmatter?]

Water

 

[Friezacel]

So basically if you are short you have an increased risk of schizophrenia due to negative reinforcement ?

 

[DarkStar]

So basically if you are short you have an increased risk of schizophrenia due to negative reinforcement ?

No, some SNPs correlate heavily with both

 

[Friezacel]

No, some SNPs correlate heavily with both

whats a SNP

 

[DarkStar]

whats a SNP

Single nucleotide polymorphisms, frequently called SNPs (pronounced “snips”), are the most common type of genetic variation among people. Each SNP represents a difference in a single DNA building block, called a nucleotide. For example, a SNP may replace the nucleotide cytosine (C) with the nucleotide thymine (T) in a certain stretch of DNA.

What are single nucleotide polymorphisms (SNPs)?: MedlinePlus Genetics

Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation in people. Learn more about SNPs and what they do.

medlineplus.gov

.

 

[WorthlessSlavicShit]

Based, Saved.

@WorthlessSlavicShit

Brutal, shit genes really do come in packages.

 

[Diddy]

Autism and schizophrenia are correlated as well

Autism spectrum disorder and schizophrenia: an updated conceptual review - PMC

Autism spectrum disorder (ASD) and schizophrenia (SCZ) are separate disorders, with distinct clinical profiles and natural histories. ASD, typically diagnosed in childhood, is characterized by restricted or repetitive interests or behaviors and ...

pmc.ncbi.nlm.nih.gov

However, youth with ASD are three to six times more likely to develop SCZ than their neurotypical counterparts, and increasingly, research has shown that ASD and SCZ converge at several levels.

 

[DarkStar]

Brutal, shit genes really do come in packages.

This is why users on here complain about having below-average penis sizes, despite the fact that their looks & NTness alone make it impossible for them to even get their foot in the door. I also believe you & others such as @PolskiKartofel have shared stuff about how looks & NT correlate

 

[manletcel1488]

Brutal.

 

[manletcel1488]

I'm not schizophrenic but I have many family members who are so maybe this makes sense.

 

[Feeshtu]

Well, I am schizophrenic and I am 5 ft. 10 in.

But, I am just one guy…..so my height doesn’t prove anything.

But, I did spend years in psych wards.
Most of the men there are short.

It is rare to see a man taller than 6 ft. 2in. in the psych wards I was at.

There are, however, a lot of guys between 5’5” and 5’10”.

 

[PolskiKartofel]

This is why users on here complain about having below-average penis sizes, despite the fact that their looks & NTness alone make it impossible for them to even get their foot in the door. I also believe you & others such as @PolskiKartofel have shared stuff about how looks & NT correlate

My attempts to find any researches were about autism and obesity correlation, but I bet when look at these more I would find some about height or general autistic phenotypes. Btw mental illnesses often cause faster ageing.

Let alone all those suicide and depression risks for autistic males and lack of any experience both in romantic and overall social fields