Serious Jews (Mainly Ashkenazim) Are Genetically Predispositioned to More Genetic Mutations

[user]

This post may be water to some, especially those of Jewish descent, but it should be worth noting that Jews (especially Ashkenazim, who are among the most admixed of the Jewish populations) are genetic filth.

Several studies have shown that Ashkenazim have a higher prevalence of certain genetic health conditions compared to the general population. This increased susceptibility is mainly due to specific genetic mutations that are more common within this group, mainly due to significant admixture with Europeans (who have a notable genetic and biological gap from Middle Easterners). Below is a table of the more common genetic disorders present in Ashkenazim:

Table - PMC

pmc.ncbi.nlm.nih.gov

It's estimated that approx. 1 in 4 and 1 in 5 Ashkenazim is a carrier for one of these genetic conditions:

Although some of these disorders in isolation would be considered rare, the overall carrier rate in this population is significant, with between 1 in 4 and 1 in 5 Ashkenazi Jews carrying a mutation for any one of these disorders.

Carrier screening in individuals of Ashkenazi Jewish descent - PMC

pmc.ncbi.nlm.nih.gov

This table provides only a glimpse of the genetic diseases to which they are predisposed. I recommend viewing this more detailed ZOGpedia page for a more comprehensive overview here. It's also strongly advised for those of Ashkenazi descent to undergo genetic testing before having children because of how dysgenic by nature they are:

We recommend that carrier screening for cystic fibrosis, Canavan disease, familial dysautonomia, and Tay-Sachs disease be offered to all Ashkenazi Jews who are pregnant or considering pregnancy, according to current American College of Medical Genetics and/or the American College of Obstetricians and Gynecologists (ACOG) guidelines.

Carrier screening in individuals of Ashkenazi Jewish descent - PMC

pmc.ncbi.nlm.nih.gov

Alongside all mentioned above, mutations in the BRCA1 and BRCA2 genes, associated with increased risks of breast and ovarian cancers, are notably more prevalent among Ashkenazi Jews. Approx. 1 in 40 Ashkenazi Jews carry a BRCA1 or BRCA2 mutation, a rate significantly higher than the general population:

The carrier frequency of the three Ashkenazi Jewish founder mutations—BRCA1 185delAG, BRCA1 5382insC, and BRCA2 6174delT—is approximately 2.5% in the general Ashkenazi Jewish population, which equates to 1 in 40 individuals.

Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer - PubMed

Approximately 12% of breast cancers in the Ashkenazi Jewish population are attributable to mutations in the BRCA1 or BRCA2 gene. Genetic testing may be useful when Jewish women with breast cancer are diagnosed before age 50 years or have a close relative with ovarian or early-onset breast...

pubmed.ncbi.nlm.nih.gov

Genetic mutations associated with an increased risk of hereditary colon cancer are more prevalent among Ashkenazim. Approx. 6-8% of Ashkenazi Jews carry the APC I1307K mutation, which increases their risk of colorectal cancer by 1.5 to 2 times:

The I1307K APC polymorphism/mutation is carried by 6-8% of Ashkenazim and increases the risk of colorectal cancer 1.5-2 fold.

Genetic factors and colorectal cancer in Ashkenazi Jews - PubMed

The observed increased incidence of colorectal cancer in Ashkenazi Jews compared to other populations is unexplained but likely has a genetic component. The I1307K APC polymorphism/mutation is carried by 6-8% of Ashkenazim and increases the risk of colorectal cancer 1.5-2 fold. There are few...

pubmed.ncbi.nlm.nih.gov

Sephardi and Mizrahi Jews are not exempt either, but they tend to have a lower prevalence of genetic diseases compared to Ashkenazim (Mizrahim with the lowest prevalence due to having the least amount of admixture). This thread is mainly about genetic diseases common among Ashkenazim, but for further reading on diseases prevalent in Sephardim and Mizrahim, I've linked this ZOGpedia page for more information here.

 

[DeadOnArrivalCel]

Facts are antisemitic

 

[user]

Facts are antisemitic

Anti-Semitic, but never a liar

 

[DarkStar]

Great thread, bookmarked & saved

Racial realism is real once again, they say the quiet part out loud as always