Experiment Are Elon and Zuck really going to fight?

[Fallenleaves]

Title.

 

[Intellau_Celistic]

No. I've already won.

 

[Immolator]

No. I've already won.

 

[Fallenleaves]

No. I've already won.

The champion is here boyos

 

[Intellau_Celistic]

It would be nice.

​

In a large-scale meta-analysis, it has been recently shown that the transcription factor 4 (TCF4) gene is among the most prominent susceptibility genes for schizophrenia. Moreover, transgenic mice overexpressing TCF4 in the brain display a reduction of sensorimotor gating measured by prepulse inhibition (PPI) of the acoustic startle response (ASR). PPI is heritable and has been established as an important translational endophenotype of schizophrenia. We therefore investigated the impact of the schizophrenia susceptibility gene TCF4 (rs9960767) on sensorimotor gating of the ASR in healthy humans and in patients with a schizophrenia spectrum disorder. We assessed PPI, startle reactivity, and habituation of the ASR in two independent samples. The first sample consisted of 107 healthy volunteers from London, UK. The second sample was a schizophrenia spectrum group (n = 113) of 73 schizophrenia patients and 40 individuals at high risk for schizophrenia from Bonn, Germany (total sample n = 220). In both samples, PPI was strongly decreased in carriers of the schizophrenia risk allele C of the TCF4 gene (meta-analysis across both samples: p = 0.00002), whereas startle reactivity and habituation were unaffected by TCF4 genotype. Sensorimotor gating is modulated by TCF4 genotype, indicating an influential role of TCF4 gene variations in the development of early information-processing deficits in schizophrenia.

The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers - PubMed​

In a large-scale meta-analysis, it has been recently shown that the transcription factor 4 (TCF4) gene is among the most prominent susceptibility genes for schizophrenia. Moreover, transgenic mice overexpressing TCF4 in the brain display a reduction of sensorimotor gating measured by prepulse...

pubmed.ncbi.nlm.nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667105/

It remains unclear whether the diversity of disorders exhibiting deficient PPI bespeaks diagnostic overlaps or comorbidities. Given the recent focus on treatments for cognitive deficits of schizophrenia independently of treating psychosis, the relationship of PPI deficits to cognitive deficits becomes of interest. Although PPI cannot be considered to be a cognitive process per se, abnormalities in pre-attentive information processing may be predictive of or lead to complex cognitive deficits. Animal models of PPI deficits produced by dopamine agonists reliably predict existing antipsychotics. Nevertheless, since neither PPI nor cognitive deficits in schizophrenia are ameliorated by standard antipsychotics, current research is exploring the predictive value of non-dopaminergic PPI models in identifying treatments for gating disturbances independently of their relevance to specific disorders. Both PPI and cognitive deficits in schizophrenia patients are not reversed by first generation antipsychotics but may be attenuated by clozapine. Similarly, effects of glutamate antagonists on symptoms in patients and PPI in animals appear to be reduced by clozapine. Hence, treatment-induced reversals of deficits in PPI produced by glutamate antagonists may provide animal, and human, models to aid in the discovery of treatments of cognitive deficits in patients already treated with existing antipsychotics.

 

[Intellau_Celistic]

It would be nice.

There's one more aspect, though.

 

[dungeondragon]

I hope Big Zuck gives him the ol' one two and sends him flying into the metaverse
Zuck is the creator of the Oculus Quest so he has my full support

 

[Fallenleaves]

I hope Big Zuck gives him the ol' one two and sends him flying into the metaverse
Zuck is the creator of the Oculus Quest so he has my full support

He'll give him the ZUCC

 

[Pancakecel]

It just sounds like something soydditors would try and arrange tbh

 

[LeFrenchCel]

No. I've already won.

Alpha male mindset

 

[SoycuckGodOfReddit]

No. I've already won.

 

[Jedi Master Cock ru]

No. I've already won.

 

[JamesMLM]

No. I've already won.

 

[Garbage Life]

It's just to promote their shitty social platforms

 

[Siegfried]

No. I've already won.

You are always a winner Inteltellau

 

[BornToLose]

Yes but in the lamest way possible.

 

[asocialcel]

Who are you guys gonna support. I'm rooting for zuck